The modification of sodium bentonite with EDTA by microwave were studied, based on the removal rate of Pb2+ as the reference index. The best modification conditions: bentonite 3g, EDTA 1g, pH value to 8 ,microwave power 500W, reaction temperature 35 ℃, microwave reaction 5min;Optimum adsorption conditions: adjust pH value to 5.83, adding 0.4 g bentonite, oscillation temperature 30 ℃, batch adsorption 40 minutes. The results showed that the Pb2+ removal rate may reach to 94% using the modified bentonite as adsorbent, the saturated adsorption weight is 29. 67mg/g.the max adsorption ability of modified bentonite is twice sodium bentonite in weight. XRD shown that the dimension of the pillared interlayer was increased from 1.51nm to 1.65nm,IR spectrum certified that appeared C-C adsorb peak, element analysis result shown that the organ C,N,H increased than the bentonite.